Open MS Word 2010, go to File Menu(Office Backstage) and select Options. Select Trust Center from the left sidebar and then click Trust Center Settings button in the main window. Now in Trust Center dialog window, select Protected View from the left sidebar and disable protected view for any desired option.
You can disable Protected View for files that failed validation, that have been downloaded from the internet, are located in unsafe locations, and/or contain attachments.
When done, hit OK. The above example is that of Word 2010, you will have to manually uncheck the options from Excel 2010, PowerPoint 2010, Outlook 2010, etc.